DIVA Nutraceuticals

DIVA Nutraceuticals


Nutraceuticals
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The increasing demand of consumers for efficient, safe and natural alternatives for non-prescribed medications push companies to strengthened their efforts in the development of highly potent active ingredients.

DIVA Expertise offers different solutions in the assistance of companies to valorize their molecules. We provide support and guidance in the development of your active compound from screening to clinical trials. This collaboration allow our partner companies to significantly shorten the time to market of their compounds.

Check our tests catalogue and Models

 

 

Our DivaGut model is the most popular for Nutraceutical development. A system combining intestinal absorption, biodisponibility, and final target assessment.

Contact us for more information.

DIVA gut 1
DIVA Pharmaceuticals

DIVA Pharmaceuticals


Pharmaceuticals
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The excessive fat mass expansion is associated with a number of disorders such as cardiovascular diseases, type 2 diabetes and dyslipidemia, together reducing life expectancy. The market of pharmaceutical products to treat obesity associated disorders represents a major research and development challenge for the pharmaceutical industry.

DIVA Expertise provides solutions to assess the effects of your molecules on adipose tissue functions and share with you our deep understanding of this tissue to resolve the most complex cases.

Check our catalogue.

DivaCaps is our most powerful tool for pharmaceuticals testing on mature adipocytes metabolism in 3D. By modulating its composition and environment, it is a suitable model for drug screening.

Contact us for more information.

Example of model used for pharmaceutical drug testing:

DIVA caps model
DIVA Cosmetics

DIVA Cosmetics


Cosmetics
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The different regulations of cosmetics and the increase of the consumers awareness push the researchers to investigate more deeply the effects of the chemicals content and the active ingredients on human health. Before selling, the companies have to proof the safety and the efficiency of their products.

DIVA Expertise proposes to major or small companies to test the cytotoxicity and the efficiency of their compounds on different experimental models with high clinical relevance. In addition, our solutions are perfect alternatives for animal testing.

Check our catalogue.

 

Different systems were developed to assess the link between subcutaneous adipose tissue and superficial skin health. 

Contact us  to select the one fitting your needs.

Example of model developped by DIVA Expertise for dermo-cosmetics:

Characterization of the extracellular matrix produced by the dermis fibroblasts

Evaluation of Hyaluronic Acid secreted in the medium

DIVA R&D

DIVA R&D


DIVA R&D
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The adipose tissue is a complexe and heterogenic organ composed by different cell types (adipocytes, precursors, immune cells, endothelial cells,…). In addition to its energy storage function, the adipose tissue plays an major endocrine role. It secretes numerous factors named adipokines as well as chemokines and inflammatory cytokines regulating the activity of several organs in human body.

At DIVA Expertise, we focus on the different functions of the adipose tissue (energy storage, endocrine, mechanical, thermogenic) by developping new experimental models allowing us to better determine the link between adipocytes and peripheral organs.

Check our catalogue.

DIVA Biomarkers

DIVA Biomarkers


Clinical analysis platform
You have the samples, we have the tools
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Clinical trials gained a strategic importance as, in addition to big pharmaceutical companies, most manufacturers consider this route to substantiate claimed health effects of their products. 

DIVA Expertise supports clinical trials by providing analysis services on Human tissues from enrolled cohorts. The adipose tissue issued form needle biopsies can be mapped and characterized morphologically, functionally and metabolically within on our platform.

The different parameters assessed :

      • Adipocyte size and distribution
      • Gene expression profile
      • Lipolytic capacity
      • Secretion profile
      • Insulin sensitivity

Check our tests catalogue and/or technical sheets

DIVA Biobank

DIVA Biobank


DIVA Biobank
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We are offering access to a large bank of Human biological samples (cells, secretions, DNA, protein extracts, and more…) for your research.

Want to participate ? You need further information about the utilization procedures ?

Just contact us !

DIVA biobank